What is an ACE Inhibitor?
Ace inhibitors (angiotensin-converting enzyme) are used in determining and monitoring blood pressure, preventing kidney disease for people with hypertension or diabetes, and treating heart failure. The ACE Inhibitors work by relaxing blood vessels and increasing the blood flow to the heart.
ACE Inhibitors were placed on the market 25 years ago, and with sales topping $3,800,000,000 (3.8 billion) and 150 million prescriptions filled in 2011 alone, millions of individuals can find themselves at risk to the adverse effects that can result.
Drugs that qualify as ACE Inhibitors include:
- Altace (Top seller)
- Lisinopril (Top seller)
- Lotrel (Top seller)
Side Effects Relating to Birth Defect Litigation
It is estimated that 2.7 million women of childbearing age were prescribed an ACE Inhibitor in 2011, and while there is no official FDA warning in regards to first trimester pregnancies, numerous studies have shown there are serious risks associated with taking an ACE Inhibitor during this stage.
The FDA currently requires ACE Inhibitors to carry a “black box” warning label in regards to using the drug in the later stages of pregnancy, and while the drugs to suggest discontinuing use while pregnant.
There is very little research that has been compiled in regards to dangers in first trimester of pregnancy but studies done have produced alarming results. In date released on June 7, 1996, it was determined that mothers who take an ACE Inhibitor during the first trimester were more than twice as likely to have their child suffer a severe brain or heart ailment. Even after these results, in a poll looking at numbers from 1995-2002, it has been determined that the number of women prescribed an ACE inhibitor, in their child bearing years, has jumped from 1.4 million in 1995, to 2.7 million in 2002.
Back in the 1990’s the FDA required the pharmaceutical companies to place warnings on ACE Inhibitors after reports of babies being harmed. The label stated the side effects that could be suffered in the last two thirds of pregnancy could include:
- Skull Deformities
- Kidney Failure
- Lung Problems
- Fetal Death
The new data suggests that ACE Inhibitors should not be taken at any point during pregnancy, or you may be at serious risk.
ACE Inhibitor Litigation
At Sheff Law, we are the Massachusetts law firm with the resources, experience, and national reputation to investigate injuries and birth defects resulting from use of ACE Inhibitors. Patients across Massachusetts and America are starting to realize some of the potential harmful consequences of taking ACE Inhibitors at any stage of a pregnancy. If you or a loved one has been injured as a result of ACE Inhibitors, contact an attorney at Sheff Law today by filling out a FREE consultation form, or call at (888) 423-4477 or 617-227-7000.
February 23rd, 2016 | Posted in Blog