Avandia Lawsuits and Avandia Liability in Massachusetts

What is Avandia?

Avandia, also known by its generic name rosiglitazone, is an antidiabetic pill taken orally, and belongs to the class of drugs known as thiazolidinediones (TZDs). Avandia increased the body’s sensitivity to insulin and assists in the management of blood sugar. This makes it effective in its treatment of Type 2 Diabetes. It is reported that worldwide over 6 million people have taken Avandia, and in 2006, sales in the United States alone reached $2,200,000,000 (2.2 billion).

On May 21, 2007 an Avandia studied was released by the New England Journal of Medicine which stated that users of Avandia could face a significant increase in the likelihood of heart attacks and cardiovascular death from prolonged exposure to the drug.

Researchers went on to review data from over 42 different clinical trials, which included over 28,000 patients, and discovered Avandia users had a 43% increase in risk of suffering a heart attack and a 64% increase in the risk of a heart related death when compared to other diabetes medications of placebos.

Lawsuits allege that GlaxoSmithKlein, the manufacturer, had access to the information over a year prior to its public release (GlaxoSmithKlein claims they knew it raised the likelihood by 30%, not the 43% alleged by the study). Having this information in hand they failed to warn the public about the potential adverse effects with continued use of Avandia, and in an attempt to drive profits, kept this information to themselves, putting the public health of individuals at great risk.

Avandia/Actos has also been known to lead to increased risk of osteoporosis, bone fractures and alleged to have been the cause of 14 known cases of liver failure (12 of which resulted in death).

Avandia Side Effects

Serious side effects can result from use of Avandia, these include, but are not limited too:

  1. Heart Attack
  2. Stroke
  3. Congestive Heart Failure
  4. Live Failure
  5. Bone Fracture
  6. Macular Edema (Vision Loss)
  7. Heart Related Death

Avandia Litigation

GlaxoSmithKlein (GSK), in an effort to keep profits high, withheld crucial information about the potential harmful effects associated with Avandia. After being approved in 1999, GSK received numerous post-marketing reports of heart attack and heart failure, but failed to initiate a large-scale credit study in order to find out the risks Avandia users were being exposed to.

At Sheff Law, we are the Massachusetts law firm with the resources, experience, and national reputation to investigate personal injuries and wrongful deaths resulting from taking Avandia. Patients across Massachusetts and America are starting to realize some of the potential harmful consequences of using Avandia. If you or a loved one has been injured as a result of Avandia, contact an attorney at Sheff Law today by filling out a FREE consultation form, or call at (888) 423-4477 or 617-227-7000.

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